Proof of Concept Safety and Efficacy Evaluation of ADL 2-1294 (Loperamide Hydrochloride Ophthalmic Solution 0.025%) for Short Term Pain Management (1999)
A Phase II, Randomized, Single-Masked (Investigator) Placebo Controlled, Parallel Evaluation of the Safety and Efficacy of Cidofovir Topical Ophthalmic Solution in the Treatment of Herpes Epithelial Keratitis
ALCON RESEARCH, LTD.
Preoperative and Postoperative Use of Nepafenac Ophthalmic Suspension, 0.1% for the Treatment of Ocular Inflammation Associated with Cataract Surgery (2004 - present)
A Three-Month, Randomized, Double-Masked, Parallel Group, Primary Therapy Study, with a Planned Nine-Month Extension, Of the Safety and IOP-Lowering Efficacy of Brimonidine Tartrate Ophthalmic Solution, 0.15% Compared to ALPHAGAN P, 0.15% In Patients with Open-Angle Glaucoma or Ocular Hypertension (2003 - present)
A Multicenter, Double-Masked, Placebo-Controlled, Dose-Response Study of the Safety and Efficacy of Once-Daily AL-12182 Ophthalmic Solution in Patients with Open Angle Glaucoma or Ocular Hypertension (2003)
An Evaluation Of The Safety And Efficacy Of Moxifloxacin Ophthalmic Solution 0.5% Versus Non-Preserved Vehicle In The Treatment Of Bacterial Conjunctivitis (2002)
Safety and Efficacy of AL-3789 Ophthalmic Suspension Versus Placebo in Primary Pteryguim Patients (1997)
Open label Efficacy and Safety Study of AL-3789 Ophthalmic Suspension in Patients with Recurrent Pteryguim (1997)
Efficacy and Safety of AL-3789 Ophthalmic Suspension in the Prevention of Neovascularization Following Recurrent Pteryguim Excision (1997)
Efficacy and Safety Evaluation of AL04943 0.1% (Olopatidine) Ophthalmic Solution Versus Placebo in Patients with Vernal Keratoconjunctivitis
A Clinical Evaluation of the Efficacy of Bion Tears, Cellufresh and AquaSite in Moderate to Severe Dry Eye Patients: A Pilot Study
Compassionate Use of Lodoxamide Ophthalmic Solution (ALOMIDE) in Patients with Vernal Keratoconjunctivitis
Efficacy and Safety Evaluation of Lodoxamide 0.1% Ophthalmic Solution versus Placebo in Vernal Keratoconjunctivitis
Efficacy and Safety of Ciprofloxacin Ophthalmic Ointment versus TOBREX Ophthalmic Ointment for Treating Bacterial Conjunctivitis in Children
Efficacy and Safety of 1.0% Rimexolone Ophthalmic Suspension versus Pred Forte, 1.0% for Treatment of Uveitis
ALLERGAN
A Masked Histological Evaluation of Trabecular Meshwork Specimens Collected From Trabeculectomy Patients With Primary Open-Angle Glaucoma Treated With Bimatoprost 0.03% Ophthalmic Solution Once-Daily (QD) For At Least Two Years Compared With Primary Open-Angle Glaucoma Patients Treated With Other Topical Ophthalmic IOP-Lowering Drugs (2004 - present)
A Clinical Study Comparing the Duration of Pre-Treatment with Ketorolac Tromethamine 0.4% (Acular LS) on the Safety and Efficacy of Cataract Surgery (2004 - present)
An Open-Label, Phase 4 Study Extension Evaluating the Efficacy of Cyclosporine 0.05% Ophthalmic Emulsion Used Twice Daily for Six Months in Patients with Moderate to Severe Keratoconjunctivitis Sicca Previously Dosed for 12 to 36 Months with Cyclosporine 0.1% (2004 - present)
A 48-Month, Multi-Center, Randomized, Double-Masked, Placebo-Controlled, Clinical Study To Evaluate The Effectiveness And Safety of Oral Memantine In Daily Doses of 20 mg And 10 mg In Patients With Chronic Open-Angle Glaucoma at Risk For Glaucomatous Progression (2001 - present)
A Multicenter, Double-Masked, Randomized, 3-Arm Parallel Study, For 3 Months (With A 9-Month, Masked Extension) Of The Safety And Efficacy Of Bimatoprost 0.03% Timolol 0.5% Combination Ophthalmic Solution Once Daily Compared With Timolol 0.5% Monotherapy Twice Daily And Bimatoprost 0.03% Monotherapy Once Daily In Patients With Glaucoma Or Ocular Hypertension (2002 - 2003)
A Multicenter, Open-Label, Phase 3 Study Extension Evaluating the Safety of Cyclosporine 0.1% Ophthalmic Emulsion Used Twice Daily for up to Three Additional Years in Patients with Moderate to Severe Keratoconjunctivitis Sicca Previously Dosed for 6 to 12 Months with Cyclosporine 0.05% or Cyclosporine 0.1%
A Multi-Center, Double-Blind, Randomized, Placebo-Controlled Study of The Safety and Efficacy of 12 Week Treatment With Tazarotene 4.5mg Capsules Once Daily Followed by a 12 Week Post-Treatment Follow-Up Period In Patients With Moderate to Very Severe Plaque Psoriasis (2002)
A Multi-Center, Double-Masked, Randomized, Parallel-Group Study to Compare the Efficacy and Safety of Two New Formulations of Emulsion Eye Drops vs. an Emulsion Vehicle Drop for One Month (with a Two-Month Masked Extension) in Subjects with Dry Eye (2001-2002)
A Multi-Center, Randomized, Double-Masked, Parallel-Group Clinical Study Evaluating The Safety And Efficacy Of Topical Ofloxacin 0.3% Ophthalmic Solution With That of Topical Trimethoprim Sulfate /Polymyxin B Sulfate Combination Ophthalmic Solutions As A Positive Control In Infants From Birth To 31 Days of Age With Bacterial Conjunctivitis (2001)
A Multi-Center, Double Masked, Randomized, Parallel Three Month Study (With Extension To 12 Months) Of The Safety And Efficacy, And Acceptability Of 0.15% And 0.2% Brimonidine-Purite Compared With 0.2% Brimonidine Administered Three-Times Daily In Subjects With Glaucoma Or Ocular Hypertension
A Clinical Study Evaluating The Ocular Safety and Efficacy Of 0.3% Ofloxacin Solution in the Treatment of Acute Bacterial Corneal Ulcers (1993-1994)
A Multicenter, Double-Masked, Randomized, Parallel Study of the Safety and Efficacy of 0.2% Brimonidine Tartrate/0.5% Timolol Combination Ophthalmic Solution Twice-Daily Compared with 0.5% Timolol Twice-Daily or Alphagan Three-Times Daily for Three Months (Plus 9-Month, Masked Extension) in Patients with Glaucoma or Ocular Hypertension
A Multicenter, Double-Masked, Randomized, Vehicle Controlled, Parallel Group Study of the Safety and Efficacy of Cyclosporine 0.05% And 0.1% Ophthalmic Emulsions Used Twice Daily for Up to One Year in Patients With Moderate to Severe Keratoconjunctivitis Sicca
A Multi-Center, Open-Label Study of Tazarotene 4.5mg Capsules Administered Once Daily For 12 Weeks Followed by a 12 Week Post-Treatment Follow-Up Period In Patients With Plaque Psoriasis Who Have No Change or an Increase in Their Overall Lesional Assessment (OLA) After 12 Weeks of Treatment in a Study of Oral Tazarotene 4.5mg Versus Placebo
AVENTIS PHARMACEUTICALS
A Phase III Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Efficacy. Safety and Dose Response Study of Ciclesonide Metered Dose Inhaler 50 µG/Day, 100 µG/Day, and 200 µG/Day (Ex-Valve) Administered Once Daily For 12 Weeks in the Treatment of Children with Persistent Asthma
BAUSCH & LOMB
A Multicenter, Randomized, Double-Masked, Controlled Study To Evaluate The Safety And Efficacy Of An Intravitreal Fluocinolone Acetonide (0.5 Or 2 Mg) Implant In Patients With Non Infectious Uveitis Affecting The Posterior Segment Of The Eye. IND # 60,000 (2002 - present)
A Randomized, Double-Masked, Multi-Center Comparison Of Aqueous Humor Concentration Of Loteprednol Etabonate Following Administration Of Bausch & Lomb Pharmaceuticals, Inc. Loteprednol Etabonate And Tobramycin Ophthalmic Suspension 0.5%/ 0.3% Or Lotemax Ò (Loteprednol Etabonate Ophthalmic Suspension, 0.5%) During Routine Cataract Surgery (2002 - 2003)
Multi-Centered Efficacy Assessment of Pheniramine Maleate 0.45% / Polyvinylpyrrolidone 2.0% Combination in the Allergen Challenge Model of Acute Allergic Conjunctivitis (1999-2000)
INSPIRE PHARMACEUTICALS, INC.
A Multi-Center, Parallel Group, Double-Masked, Randomized, Placebo-Controlled Study of Multiple Ocular Instillations of Diquafosol Tetrasodium Ophthalmic Solution, 2% in Subjects with Dry Eye Disease (2004 - Present)
A Multi-Center, Double-Masked, Randomized, Placebo-Controlled, Dose-Ranging Study of Multiple Ocular Instillations of INS 365 Ophthalmic Solution vs. Placebo in Subjects with Moderate to Severe Dry Eye Disease (2001 - 2002)
ISIS PHARMACEUTICALS
A Study for the Safety and Efficacy of Intravitreal Isis 2922 Injections in Acquired Immune Deficiency Syndrome (AIDS) Patients With Cytomegalovirus (CMV) Retinitis
ISTA PHARMACEUTICALS
Efficacy and Safety of Topical Bromfenac Ophthalmic Solution, 0.1% Vs. Placebo for Treatment of Ocular Inflammation following Cataract Surgery (2003)
OTSUKA
A Phase II Multicenter, Randomized, Double-Masked, Dose- Response, Placebo-Controlled, Parallel-Group Study of the Safety and Efficacy of Rebamipide Sterile Ophthalmic Suspension in the Treatment of Dry Eye
PHARMACIA & UPJOHN
A Comparison of Fixed Combination of Latanoprost and Timolol with Fixed Combination of Dorzolamide and Timolol (COSOPT) in Patients with Elevated Intraocular Pressure. A Three-month Masked Evaluator, Phase IIIb, Multicenter Study in the United States (2001)
A Comparison of Latanoprost with Travaprost and Bimatoprost in Patients with Elevated Intraocular Pressure. A Twelve- Week, Masked Evaluator, Phase IV, Multicenter Study in the United States
PHARMOS CORPORATION
Comparison of the Safety and Efficacy of Lotemax and Prednisolone Acetate in Acute Anterior Uveitis (1996)
SANTEN, INC.
A Prospective, Randomized, Parallel-Group, Multi-Center, Observer-Masked Trial Comparing The Efficacy And Safety Of 0.5% Levofloxacin With 1.0% Prednisolone Acetate To 0.5% Levofloxacin Monotherapy, 1.0% Prednisolone Acetate Monotherapy, And Vehicle, For The Treatment Of Peripheral Inflammatory Keratitis (2002 - present)
A Prospective, Randomized, Parallel-Group, Multi-Center, Double-Masked Trial Comparing the Efficacy and Safety of 1.5% Levofloxacin Ophthalmic Solution with 0.3% Ofloxacin Ophthalmic Solution for Treating Bacterial Keratitis (2001-2002)
SENJU PHARMACEUTICALS
A Phase III Multicenter, Randomized, Double-Masked, Parallel Study To Compare The Safety and Efficacy Of 0.3% Gatifloxacin Ophthalmic Solution With That of 0.3% Ofloxacin Ophthalmic Solution in The Treatment of Acute Bacterial Conjunctivitis
SMITHKLINE BEECHAM PHARMACEUTICALS
A Double Masked, Double Dummy, Randomized, Acyclovir Controlled, Parallel Group Study To Compare The Efficacy And Safety of Famciclovir With Acyclovir In The Treatment Of Patients With Ophthalmic Zoster (1997)
TOUCH SCIENTIFIC, INC.
Clinical Comparison of the Touch LactoCard System to the Touch Lactoplate System for the Measurement of Lactoferrin in Tears as an Aid in the Diagnosis of Dry Eye of Keratoconjunctivitis Sicca (1993-1994)